The MV Agusta F4 is a four-cylinder sport bike made by MV Agusta from 1999 until 2018.

The MV Agusta F4 is an inline four-cylinder sport bike made by MV Agusta from 1999 until 2018. It was the motorcycle that launched the resurrection of the brand in 1998. The F4 was created by motorcycle designer Massimo Tamburini at CRC (Cagiva Research Center), following his work on the Ducati 916. The F4 has a single-sided swingarm, large diameter (49 or 50 mm (1.9 or 2.0 in)) front forks and traditional MV Agusta red and silver livery. The F4 engine is also one of the few production superbikes to have a hemi-spherical cylinder head chamber design with 4 valves per cylinder.

MV Agusta is a high end motorcycle manufacturer founded by Count Domenico Agusta on 19 January 1945 as one of the branches of the Agusta aircraft company near Milan in Cascina Costa, Italy. The abbreviation MV stands for Meccanica Verghera, the hamlet where the first MVs were made.

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